Patents and Published Applications Developed for PharmaDirections' Clients

1. R. Soltero, N. Ekwirube, F. Opawale, A. Hickey, B. Rehaender, L. Bovet, "Pharmaceutical compositions of calcitonin drug-oligomer conjugates and methods of treating diseases therewith" United States Patent 6,770,625
   
   
2. R. Soltero, N. Ekwirube, B. Rehaender, L. Bovet, A. Hickey, "Pharmaceutical Compositions of Insulin Drug-Oligomer Conjugates and Methods of Treating Diseases Therewith" United States Patent 6,867,183
   
   
3. R. Soltero, B. Radhakrishnan, N. Ekwirube, "Methods of Synthesizing Insulin Polypeptide-Oligomer Conjugates, and Proinsulin Polypeptide-Oligomer Conjugates and Methods of Synthesizing Same" United States Patent 6,913,903
   
   
4. R. Soltero, N. Ekwirube, F. Opawale, B. Rehaender, A. Hickey, "Pharmaceutical compositions of drug-oligomer conjugates and methods of treating disease therewith” United States Patent 7,030,082
   
   
5. R. Soltero, B. Radhakrishnan, N. Ekwirube, “Insulin polypeptide-oligomer conjugates, proinsulin polypeptide-oligomer conjugates and methods of synthesizing same" United States Patent 7,166,571
   
   
6. R. Soltero, B. Radhakrishnan, N. Ekwirube, B. Rehaender, A. Hickey, L. Bovet, "Pharmaceutical compositions of insulin drug-oligomer conjugates and methods of treating diseases therewith" United States Patent 7,196,059
   
   
7. B. Radhakrishnan, R. Soltero, N. Ekwirube, M. Puskas, D. Sangal, "Insulin polypeptide-oligomer conjugates, proinsulin polypeptide-oligomer conjugates and methods of synthesizing same" United States Patent 7,312,192
   
   
8. B. Radhakrishnan, R. Soltero, N. Ekwirube, "Methods of synthesizing insulin polypeptide-oligomer conjugates, and proinsulin polypeptide-oligomer conjugates and methods of synthesizing same" United States Patent 7,368,260
   
   
9. R. Soltero, N. Ekwuribe, F. Opawale, B. Rehlander, A. Hickey, L. Bovet, "Pharmaceutical compositions of drug-oligomer conjugates and methods of treating diseases therewith" United States Patent Application 20030069170
   
   
10. J. G. Still, R. Soltero, et al., "Methods of Reducing Hypoglycemic Episodes in the Treatment of Diabetes Mellitus" United States Patent Application 20040038867
    
    
11. F. Opawale, R. Soltero, "Micro-particle fatty acid salt solid dosage formulations for therapeutic agents" United States Patent Application 20050095216
    
    
12. R. Soltero, "Method for administering medicaments to subjects with swallowing difficulties and disorders" United States Patent Application 20070196495
    
    
13. A. McKinney, G. Tollefson, S. Yau, R. Vladyka, R. Soltero, "Sustained Release Formulations of Zonisamide" United States Patent Application 20070148237
    
    
14. G. Tollefson, A. McKinney. M. Higgin, J. McCall, "Compositions for affecting weight loss" United States Patent Application 20070117827
    
    
15. A. McKinney, G. Tollefson, R. Soltero, E. Dunzo, "Sustained Release Formulations of Naltrexone" United States Patent Application 20070281021
    
    
16. A. McKinney, G. Tollefson, E. Weber, R. Soltero, "Methods for Administering Weight Loss Medications" United States Patent Application 20080110792
    
    
17. A. McKinney, G. Tollefson, E. Weber, R. Soltero, "Layered Pharmaceutical Formulations" United States Patent Application 20080113026
    
    
18. R. Soltero, "System and Method for Developing and Managing a Manufacturing Process" United States Patent Application 20080097804
    
    
19. R. Soltero, B. Rehlander, "A Method for Stabilizing Acidic and Alkaline Labile Pharmaceutical Products" PTO Application Number 61059290

Other Issued Patents and Published Patent Applications with PDI Staff as Inventors

1. US 4,546,193: Antiarrhythmic cyclooct[b]indoles
   
   
2. US 4,638,008: Antiarrhythmic agents
   
   
3. US 4,665,227: N-substituted-4(3)-nitrobenzene sulphonamides
   
   
4. US 4,698,445: 4-amino benzenesulfonamides
   
   
5. US 4,721,809: Alkylsulfonamido or perfluoroalkylsulfonamido benzenesulfonamides
   
   
6. US 4,794,196: N-aminoalkylperfluoroalkanoylaminobenzene-sulfonamide anti-arrhythmic agents
   
   
7. US 5,002,949: 5-substituted-6-aminopyrimidine derivatives
   
   
8. US 5,144,072: Anti-arrhythmic agents
   
   
9. US 6,037,358: Decongestant/antihistaminic compositions
   
   
10. US 6,287,597: Decongestant/antihistaminic compositions
    
    
11. US 6,306,904: Antihistaminic/antitussive compositions
    
    
12. US 6,586,469: Antihistaminic/antitussive compositions
    
    
13. US 6,630,498: Eprosartan arginyl charge-neutralization-complex and a process for its preparation and formulation
    
    
14. US D383,533: Pharmaceutical tablet
    
    
15. US D383,534: Pharmaceutical tablet